Alzheimer’s: Are we on the right path to new drugs?

Posted on Leave a commentPosted in Epidemiology, Genetics, Immune System, Medical Advice, Medical News, Mental Health, Nervous System, Neurology, Pharmaceuticals, Pioneering Technology

With the number of people living with Alzheimer’s disease expected to almost triple by 2050, the race is on to find a treatment that can prevent or slow the condition. But last week saw another crack emerge in the already rocky path toward an effective Alzheimer’s medication; pharmaceutical giant Eli Lilly announced the failure of […]

Scientists engineer therapeutic system with two arms to get better hold on cancer target

Posted on Leave a commentPosted in Biomedical Science, Cancer, DNA, Genetics, Medical News, Pharmaceuticals, Pioneering Technology

Scientists have engineered a sort of biological barbell that can get inside cancer cells and do damage to two proteins that work independently and together to enable cancer’s survival and spread. Their therapeutic strategy includes a molecule on either end called an aptamer that targets, in this case, prostate cancer. Sandwiched in between are two […]

Antibiotic resistance: ‘Snot wars’ study yields new class of drugs

Posted on Leave a commentPosted in Antibiotics, Bacteria, Biomedical Science, Biotechnology, DNA, Epidemiology, Evolution, Genetics, Immune System, Medical News, Pharmaceuticals

A new class of antibiotics has been discovered by analysing the bacterial warfare taking place up people’s noses, scientists report. Tests reported in the journal Nature found the resulting drug, lugdunin, could treat superbug infections. The researchers, at the University of Tubingen in Germany, say the human body is an untapped source of new drugs. The last new […]

Patch delivers drug, gene, and light-based therapy to tumor sites

Posted on Leave a commentPosted in Aging/Growth, Biomedical Science, Biotechnology, Cancer, Dermatology, DNA, Genetics, Immune System, Medical History, Medical News, Pioneering Technology

In mice, device destroyed colorectal tumors and prevented remission after surgery Approximately one in 20 people will develop colorectal cancer in their lifetime, making it the third-most prevalent form of the disease in the U.S. In Europe, it is the second-most common form of cancer. The most widely used first line of treatment is surgery, […]

Portable diagnostic tool rapidly detects Zika virus

Posted on Leave a commentPosted in Biomedical Science, Biotechnology, Diagnostics, DNA, Epidemiology, Expert Contributor, Genetics, Immune System, Medical News, Pharmaceuticals, Pioneering Technology, Viruses

In the earliest days of the most recent Zika virus pandemic, researchers around the world set out to understand every facet of a contagion that seemed almost uncontrollable. While some researchers and physicians studied the pathophysiology of the virus and the seemingly minor illness it caused, ecologists and entomologists sought out the virus’s origin and […]

Simple Method Developed to Characterize Immune Cells in Tumors

Posted on Leave a commentPosted in Biomedical Science, Cancer, Diagnostics, Genetics, Immune System, Medical News, Microscopy, Pioneering Technology

Despite recent achievements in the development of cancer immunotherapies, only a small group of patients typically respond to them. Predictive markers of disease course and response to immunotherapy are urgently needed. To address this need, researchers at The Tisch Cancer Institute (TCI) at the Icahn School of Medicine at Mount Sinai have developed a new […]

Herpesviruses could be eradicated with gene-editing technique

Posted on Leave a commentPosted in Biomedical Science, Biotechnology, Dermatology, DNA, Genetics, Immune System, Medical News, Microscopy, Pharmaceuticals, Viruses

Herpesviruses are responsible for an array of infections and diseases, including cold sores, shingles, genital herpes, and even some forms of cancer. Now, new research reveals how a revolutionary genome-editing technique called CRISPR/Cas9 could eliminate these viruses once and for all. Researchers say the CRISPR/Cas9 gene-editing tool shows promise for the elimination of herpesviruses. Study […]

Possible psoriasis drug target identified

Posted on Leave a commentPosted in Autoimmune, Biomedical Science, Dermatology, Diagnostics, DNA, Epidemiology, Genetics, Immune System, Medical News, Pharmaceuticals, Pioneering Technology

Researchers have discovered a protein involved in psoriasis, a highly common skin disease, opening up new potentials for therapy. Psoriasis is one of the most common human skin diseases. People with severe cases sometimes resort to immunosuppressive treatment to quell the skin scaling, itching and joint arthritis that are hallmarks of the disorder. But long-term […]

Novel insight into metastasis could offer new treatments

Posted on 1 CommentPosted in Anatomy, Biomedical Science, Cancer, Diagnostics, DNA, Genetics, Medical News, Pioneering Technology

Researchers from the United Kingdom may have made a breakthrough in cancer treatment, after discovering an unusual mechanism by which cancer cells spread and survive in the body. In a study published in Nature Communications, researchers reveal how two molecules join forces to help cancer cells survive as they metastasize. Researchers have uncovered a new […]

Research may point to new ways to deliver drugs into bacteria

Posted on Leave a commentPosted in Antibiotics, Bacteria, Biomedical Science, Diagnostics, DNA, Genetics, Immune System, Medical News, Microscopy

An exhaustive look at how bacteria hold their ground and avoid getting pushed around by their environment shows how dozens of genes aid the essential job of protecting cells from popping when tensions run high. For centuries, biologists have considered cells the irreducible unit of life, and cells require various types of envelopes to contain […]

Cancer-preventing protein finds its own way in our DNA

Posted on Leave a commentPosted in Biomedical Science, Cancer, Diagnostics, DNA, Genetics, Immune System, Medical News

Geneticists from KU Leuven, Belgium, have shown that tumour protein TP53 knows exactly where to bind to our DNA to prevent cancer. Once bound to this specific DNA sequence, the protein can activate the right genes to repair damaged cells. Researchers from KU Leuven, Belgium, have shown that the protein TP53 knows exactly where to […]

Engineers develop a new biosensor chip for detecting DNA mutations

Posted on Leave a commentPosted in Biomedical Science, Biotechnology, Diagnostics, DNA, Genetics, Implants, Medical News, Pioneering Technology, Robotics

Bioengineers at the University of California, San Diego have developed an electrical graphene chip capable of detecting mutations in DNA. Researchers say the technology could one day be used in various medical applications such as blood-based tests for early cancer screening, monitoring disease biomarkers and real-time detection of viral and microbial sequences. The advance was […]

Novel blood test could diagnose diseases with no known antigens

Posted on Leave a commentPosted in Autoimmune, Bacteria, Biomedical Science, Cancer, Cardiovascular, Diagnostics, Genetics, HIV, Immune System, Medical News, Mental Health, Pioneering Technology

It may one day be possible to identify cancer, autoimmune diseases, and a wealth of other conditions from a single drop of blood, after a team from the University of Pittsburgh reveals the creation of a test that holds promise for such a feat. Researchers have created a blood test that they say could diagnose […]

New treatment can ‘halt’ multiple sclerosis, says study

Posted on Leave a commentPosted in Autoimmune, Biomedical Science, Genetics, Immune System, Medical News, Nervous System, Neurology, Pioneering Technology

Aggressive chemotherapy followed by a stem cell transplant can halt the progression of multiple sclerosis (MS), a small study has suggested. MS causes the body’s own immune system to attack the lining of nerves in the brain and spinal cord, Credit: Thinkstock The research, published in The Lancet, looked at 24 patients aged between 18 […]

When it comes to developing stem cell treatments, seeing is half the battle

Posted on Leave a commentPosted in Aging/Growth, Biomedical Science, Biotechnology, DNA, Genetics, Medical News, Pioneering Technology, Stem Cells

Stem cell therapies hold great promise in treating a variety of diseases, but in order to develop them researchers must first be able to monitor them inside the body. Enter the contrast agent. “Often things go wrong right away when stem or therapeutic cells are injected into the body because some cells can migrate, while […]

Parkinson’s connection to faulty mitochondria investigated

Posted on Leave a commentPosted in Aging/Growth, Anatomy, Biomedical Science, Diagnostics, DNA, Genetics, Medical News, Mental Health, Neurology

Researchers from the University of Pittsburgh School of Medicine have gleaned new insights into the cellular biochemistry that underpins Parkinson’s disease. The team hopes that these new clues will help design effective drugs in the future. Parkinson’s disease (PD) is a degenerative condition that affects the dopamine-producing cells in the human brain. Credit: http://bit.ly/22Zjynk Affecting […]

After secret Harvard meeting, scientists announce plans for synthetic human genomes

Posted on Leave a commentPosted in Biomedical Science, Biotechnology, Diagnostics, DNA, Genetics, Medical History, Medical News, Pioneering Technology

Three weeks ago, 130 scientists, entrepreneurs and policy leaders held an invitation-only, closed-door meeting at Harvard University to discuss an ambitious plan to create synthetic human genomes. Now, after a flurry of criticism over the secrecy of the effort, the participants have published their idea, declaring that they’re launching a project to radically reduce the […]

DNA ‘tape recorder’ to trace cell history

Posted on 2 CommentsPosted in Biomedical Science, Biotechnology, DNA, Genetics, Medical News, Pioneering Technology

Researchers have invented a DNA “tape recorder” that can trace the family history of every cell in an organism. The scientists proved the technique using a classic laboratory organism – the zebrafish. Credit: SCIENCE PHOTO LIBRARY The technique is being hailed as a breakthrough in understanding how the trillions of complex cells in a body are descended […]

Scientists have performed the first trials of a ‘universal cancer vaccine’

Posted on 2 CommentsPosted in Biomedical Science, Biotechnology, Cancer, DNA, Genetics, Immune System, Medical News, Pioneering Technology

Scientists just took a big, “very positive” step towards developing what could be the first ‘universal cancer vaccine’. Credit: Cancer Research UK via Henry Scowcroft/YouTube The results from early trials in humans, along with research in mice, have just been published, and they suggest that the new technique could be used to activate patients’ immune […]

The superbug that experts have been dreading has just reached the US

Posted on Leave a commentPosted in Antibiotics, Bacteria, Biomedical Science, Diagnostics, DNA, Epidemiology, Genetics, Immune System, Medical News, Microscopy, Pharmaceuticals

A type of bacteria that’s resistant to the last antibiotic we have left against superbugs has made it to the US, and it signals something doctors have been dreading for years – the end for antibiotics. The bacterium, a strain of Escherichia coli, was found in the urine of a Pennsylvania woman. The strain is […]

Early human embryo

Controversial: In Search For Cures, Scientists Create Embryos That Are Both Animal And Human

Posted on Leave a commentPosted in Biomedical Science, Biotechnology, DNA, Genetics, Medical History, Medical Law, Medical News, Microscopy, Pioneering Technology, Reproduction, Stem Cells, Surgery, Transplants

A handful of scientists around the United States are trying to do something that some people find disturbing: make embryos that are part human, part animal. Credit: Jeannie Phan for NPR The researchers hope these embryos, known as chimeras, could eventually help save the lives of people with a wide range of diseases. One way […]

microbes

Beware of microbial traffic jams

Posted on Leave a commentPosted in Bacteria, Biomedical Science, Genetics, Medical News, Microscopy, Reproduction

Biophysicist finds that rapidly proliferating yeast pack quite a punch: Up to 150 psi When tiny microbes jam up like fans exiting a baseball stadium, they can do some real damage. A wild strain of yeast growing in a tiny chamber gradually fills the space and, because the yeast cells are so sticky, easily clog […]

Breast cancer: Scientists hail ‘milestone’ genetic find

Posted on Leave a commentPosted in Aging/Growth, Cancer, Diagnostics, DNA, Epidemiology, Genetics, Medical News

Scientists say they now have a near-perfect picture of the genetic events that cause breast cancer. Credit: SPL The study, published in Nature, has been described as a “milestone” moment that could help unlock new ways of treating and preventing the disease. The largest study of its kind unpicked practically all the errors that cause […]

‘Youth gene’ identified by researchers

Posted on Leave a commentPosted in Aging/Growth, Dermatology, DNA, Epidemiology, Genetics

The quest to find the fountain of eternal youth is probably as old as aging itself. New research, published in Current Biology, moves humanity another small step closer to the prize. A gene has been identified that plays a role in keeping people looking younger than their years. Comparing the face of an average 47-year-old (L), […]

Editing an End to Malaria?

Posted on Leave a commentPosted in Biomedical Science, Epidemiology, Genetics, Immune System, Medical News, Parasites, Pharmaceuticals, Pioneering Technology

The promise, and possible perils, of a new genetic tool Flaminia Catteruccia, shown here in the insectary at Harvard’s school of public health, is plumbing the mysteries of mosquito sex. Photograph by Stu Rosner. At Harvard, experiments involving mosquito sex are the purview of Flaminia Catteruccia, director of the insectary at the Harvard Chan School of […]

Synthetic Biology

Posted on Leave a commentPosted in Bacteria, Biomedical Science, Biotechnology, DNA, Genetics, Medical News, Pharmaceuticals, Pioneering Technology

The world of medicine is a big one. Far bigger than most of us can even begin to imagine. During the next few weeks, we will talk about some of the less talked about branches of medicine like Biomedical Research, Biotechnology, and Bioengineering.  http://sustainablepulse.com/wp-content/uploads/2015/06/synthetic-biology.jpg Today’s article is on a relatively new field called Synthetic Biology. […]

dna

Scientists store digital images in DNA, and retrieve them perfectly

Posted on Leave a commentPosted in Biomedical Science, Biotechnology, DNA, Genetics, Medical News, Pioneering Technology

Researchers have developed one of the first complete systems to store digital data in DNA — allowing companies to store data that today would fill a big box store supercenter in a space the size of a sugar cube. Technology companies routinely build sprawling data centers to store all the baby pictures, financial transactions, funny […]

Methods used to create textiles also could help manufacture human tissues

Posted on Leave a commentPosted in Biomedical Science, Biotechnology, Genetics, Pioneering Technology

Bioengineers determine textile manufacturing processes ideal for engineering tissues needed for organ and tissue repair Tissue engineering is a process that uses novel biomaterials seeded with stem cells to grow and replace missing tissues. When certain types of materials are used, the ‘scaffold’ that are created to hold stem cells eventually degrade, leaving natural tissue […]

A Potential HIV Cure: Removing HIV DNA From Immune Cell Genome Prevents Reinfection

Posted on Leave a commentPosted in Biomedical Science, DNA, Genetics, HIV, Immune System, Medical News, Viruses

In the past four years we’ve heard stories of babies born with HIV who were reportedly cured, only to have the disease return months later. In an effort to find a cure for HIV/AIDS and bring the epidemic to an end, scientists at Temple University have designed a specialized gene editing system that could pave the way to an eventual cure. http://blogs.elca.org/hungerrumblings/files/2011/06/hiv-virus.gif […]

Artificial DNA folds into parcels that can survive inside us

Posted on Leave a commentPosted in Biomedical Science, Biotechnology, DNA, Genetics, Medical News, Pioneering Technology

This tiny origami below has a lasting appeal. Strands of artificial genetic material have been folded into 3D shapes of our own choosing for the first time. These parcels could be used to carry medicinal cargoes inside the body. Drug delivery vessels? A.Taylor, F. Beuron, S-Y. Peak-Chew, E.P. Morris, P. Herdewijn, P. Holliger. Naturally occurring nucleic […]

e-coli

Genetically modified E. coli pump out morphine precursor

Posted on 1 CommentPosted in Bacteria, Biomedical Science, Biotechnology, Genetics, Medical News, Pain, Pharmaceuticals

Bacteria engineered in Japan yield 300 times more opiates than yeast. A common gut microbe could soon be offering us pain relief. Japanese bioengineers have tweaked Escherichia coli genes so that they pump out thebaine, a morphine precursor that can be modified to make painkillers. The genetically modified E. coli produces 300 times more thebaine […]

neurons

First drug to reverse Huntington’s disease begins human trials

Posted on Leave a commentPosted in Biomedical Science, Genetics, Medical News, Neurology

The new drug, called IONIS-HTTRx, silences the gene known to be responsible for the production of a protein which causes Huntington’s A drug which appears to reverse Huntington’s disease is being trialled in humans after proving successful in monkeys and mice. The new drug, called IONIS-HTTRx, silences the gene known to be responsible for the […]

There’s a new approach to fighting cancer: keeping cancer cells alive

Posted on Leave a commentPosted in Cancer, Genetics, Medical News, Pioneering Technology

While conventional cancer chemotherapy involves administering the maximum tolerated dose of medication to the patient in the hope of destroying as many cancer cells as possible, a less aggressive approach to fighting the disease could offer improved outcomes, according to a new study. Researchers in the US have developed a new approach to fighting cancerous […]

Genetically Modified Mosquitoes to Fight Zika?

Posted on Leave a commentPosted in DNA, Genetics, Medical News, Viruses

The goal: Sterile males would mate with females that carry the germ suspected of causing birth defects  As the Zika virus continues to spread fear and potentially devastating health problems throughout Latin America and the Caribbean, scientists are weighing the use of a controversial weapon – genetically modified mosquitoes.  The mosquito-borne Zika virus is thought – but […]

One Blood Type Increases Memory Problems; Research Examines Dementia Risk

Posted on Leave a commentPosted in DNA, Genetics, Medical News, Neurology

What can our blood tell us about our memory and thinking process? The red liquid coursing through our veins has more power over our brain function than scientists originally thought. A three-year research study has found individuals with blood type AB were twice as likely to experience memory problems as those with type O blood. […]

First children diagnosed in DNA project

Posted on Leave a commentPosted in DNA, Genetics, Medical News, Pioneering Technology

The first children with debilitating “mystery” diseases have finally been given a diagnosis as part of a huge scheme to analyse people’s DNA. Georgia Walburn-Green with mum Amanda and dad Matt  Four-year-old Georgia Walburn-Green’s damaged eyes and kidneys and her inability to talk had baffled doctors. She is one of the first to have her […]

New Superbug’s Genetic Trick Could Help It Spread

Posted on Leave a commentPosted in DNA, Genetics, Medical News

Health experts are keeping a close eye on a type of antibiotic-resistant bacteria called CRE that, while still rare, has the potential to become more widespread in the United States. This type of bug includes some strains of Escherichia coli and other bacteria. This image shows two rod-shaped bacteria called Klebsiella pneumoniae that are resistant […]